It may be the headphones as they use a USB port.Try unplugging them and see if Audiosurf will start.If that works then it may be possible to plug them back in after Audiosurf has started, it may not. Windows can be funny about these sorts of things.It might be worth trying unplugging all USB devices except your mouse as something is clearly messing about with direct input that specific programs can't cope with.
No problem.It does seem Quest3D has issues with USB devices it can't identify. I think this is the first time we've had headphones as the problem though, it's usually an odd controller input like a 3rd party guitar controller.