I'm also noting serious FPS issues in comparison to the beta. I notice I get slightly better results running it at my native res (1280x1024) in a fullscreen rather than in the default settings of windowed all all the settings off.
amd athlon64 3800+ single
1GB DDR3200 Dual Channel
256MB 7900GS
XP Pro SP2 32Bit
X-fi xtrememusic
the hard drive i'm running it on is a 160GB IDE (on it's own bus) and an 8MB cache with almost nothing on it, no spyware, no viruses, nothing, pretty recent install too.
I've tried defragging, restarting, making sure there were no weird global settings in my 7900GS drivers (I am using the very latest). I'm not using any fancy mouse drivers, although I do use the mouse.
The thing i notice, is if you move the mouse too quick, at any setting, the framerate drops about 10-20FPS. Fullscreen with all the options, gives me about 30-40FPS. And it looks great, however whenever the ship goes over a "hump" where the beat would be, thats when the framerate takes a hit. So compared to in the beta, where you would have been able to easily catch the colors (lets say in ninja mono) this would have been very easy. However now, the lag makes enough of a difference that it keeps from the flow and messes you up. If you had to think of it in this sense:
aaaaaaaaaaaaaaKJSDKLJFKaaaaaaaaaaaaaKSJDLFLSDLaaaaaaaaaaaaaaaaaKSJDLFKSLJDaaaaaaaaa
where the continuous 'a' is steady framerate, and the capitals are not. they tend to be tied with the beats rather than the flow of traffic.
there is no framerate difference running at a very low res, to a very high res on my machine, at whatever settings really, it just seems to take dips when there is visual beat. (the default settings windowed give me about 40FPS, full screen native res with all settings off gives about 50-60FPS, all settings on at native res give about 30-40) So in this case dodging grey's and trying to collect colors has gone from 'obtainable' to 'frustrating'.