Do you mean this by blank screen?
Because then I have the same problem as you.
I've tried uninstalling and then reinstalling but that didn't work for me.
What did work however was to start it as administrator, but before it worked as normal user too.
I really like to see this fixed as I don't want to run the game as administrator all the time.
My laptop crashed while playing audiosurf so I resetted my laptop and then this problem appeared.
I'm using Windows Vista SP1 RC, if that helps for you.
EDIT: I found the problem myself
deleting the folder C:\Users\$USERNAME$\AppData\Local\VirtualStore\Program Files\Audiosurf did the trick. However I suggest you back it up first in case this is'nt the fix. I lost all my offline scores and have to load all songs from start again, but at least I can play it again, withourt running as administrator!
I hope this works for you too!